The Human Druggable CRISPR Library

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The Human Druggable CRISPR Library

The Human Druggable CRISPR Library

Catalog# LIBR-H027-P002 LIBR-H027-P100 LIBR-H027-P200 LIBR-H027-P500

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Instruction

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The CRISPR knockout library targets 1,980 human druggable genes with a total of 10,000 knockout plasmid vectors, of which 5 different gRNA vectors are designed for each gene, in addition to 100 control vectors targeting intergenic sequences. The library uses YCS-LV001 as the backbone, which is a single-plasmid system that expresses both gRNA and Cas9 gene and can be used directly.
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Product Information

Product Name
The Human Druggable CRISPR Library
Organism
Human
Library Type
Knockout Library
Plasmid System
Single-plasmid System
Virus Packaging System
3rd Lentivirus Packaging System
Targeted Genes
1980
gRNA Number
10000
Non-targeting gRNA Number
100
Label
Puro
Vector Formula
lentiCRISPR v2 vector formula
Click to view the full image
CRISPR iScreen™ Product Strength
  • 35+ Libraries
    100+ Cas9 cell lines for screening
    35+ Library types in stock, fulfilling different research needs Cas9 cells with high activity, good cell condition, easily accelerate CRISPR library construction.
    1
  • Plasmid
    Coverage>99%, uniformity<10
    The use of self-developed library specific competent cell makes it easier to capture exogenous DNA, with high transformation efficiency and low mutation risk.
    2
  • Cell Pool
    Coverage rate up to 99%
    Exclusive cell pool preparation process can achieve large-scale and standardized production of library cell pool, achieving fewer differences between batches and high repeatability.
    3
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The Cas9 cell lines in our cell bank can stably express Cas9 protein. So gene knockout can be achieved by transfecting gRNA. Simultaneously transfecting gRNA and donor DNA can achieve gene knock-in/point mutation, effectively improving experimental efficiency.
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