Nanoparticles targeting mutant p53 overcome chemoresistance and tumor recurrence in non-small cell lung cancer
Author: Yu-Yang Bi, Qiu Chen, Ming-Yuan Yang
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Age-related self-DNA accumulation may accelerate arthritis in rats and in human rheumatoid arthritis
Author: Wei-Dan Luo, Yu-Ping Wang, Jun Lv
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High Throughput Confined Migration Microfluidic Device for Drug Screening
Author: Zihan Yang, Zhihang Zhou, Tongxu Si
A Membrane‐Targeting Aggregation‐Induced Emission Probe for Monitoring Lipid Droplet Dynamics in Ischemia/Reperfusion‐Induced Cardiomyocyte Ferroptosis
Author: Yihui Wang, Yuan Song, Lingling Xu
LIMP-2 enhances cancer stem-like cell properties by promoting autophagy-induced GSK3β degradation in head and neck squamous cell carcinoma
Author: Yuantong Liu, Shujin Li, Shuo Wang
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Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
Author: Yuan-Tong Liu, Lei Chen, Shu-Jin Li
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A new intracellularly regulated release pattern controlled by coordinated carrier cracking and drug release
Author: Xinyue Zhang ，Ye He ，Zhiqi Wang ，Ying Zhang ，Wen Guo ，Shuai Li ，Xinyu Wang ，Yuling Mao ，Siling Wang
Aberrant Nuclear Export of circNCOR1 Underlies SMAD7-Mediated Lymph Node Metastasis of Bladder Cancer
Author: Mingjie An # 1 2 3, Hanhao Zheng # 1 2 3, Jian Huang # 1 2 3
Elevated expression of WSB2 degrades p53 and activates the IGFBP3-AKT-mTOR-dependent pathway to drive hepatocellular carcinoma
Author: Xun Li, Cheng-Cheng Zhang, Xiao-Tong Lin
The absence of thioredoxin-interacting protein in alveolar cells exacerbates asthma during obesity
Author: Ji-Soo Jeong, Jeong-Won Kim, Jin-Hwa Kim
Transcription factor 12-mediated self-feedback regulatory mechanism is required in DUX4 fusion leukaemia
Author: Zhihui Li, Minghao Jiang, Junfei Wang
FBXO43 promotes cell cycle progression in cancer cells through stabilizing SKP2
Author: Liyun Zheng , Jiajia Shen，Yang Chen ，Jingyu Lin ，Pengyu Li ，Xiaoli Zhao ，Hangjiang Ren ，Yi Sun ，Zhen Wang
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Glutamine inhibition combined with CD47 blockade enhances radiotherapy-induced ferroptosis in head and neck squamous cell carcinoma
Author: An Song, Lei Wu, Bo-Xin Zhang
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TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway
Author: Rong Li, Jing Zhang, Qiong Wang
Six-hour time-restricted feeding inhibits lung cancer progression and reshapes circadian metabolism
Author: Dan Shi, Gaofeng Fang, Qianyao Chen
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Ciliogenesis-associated Kinase 1 Promotes Breast Cancer Cell Proliferation and Chemoresistance via Phosphorylating ERK1.
Author: Yanling He, Xinyuan Zhang, Weijun Pan
Epstein-Barr Virus Synergizes with BRD7 to Conquer c-Myc-Mediated Viral Latency Maintenance via Chromatin Remodeling
Author: Shen Li, Li Yang, Yanling Li
GSDME Is Related to Prognosis and Response to Chemotherapy in Oral Cancer
Author: S. Wang*, M.J. Zhang*, Z.Z. Wu
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Physical exercise attenuates age-related muscle atrophy and exhibits anti-ageing effects via the adiponectin receptor 1 signalling
Author: Yuan-Li Chen, Yi-Cheng Ma, Jie Tang
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Killing two birds with one stone: Siglec-15 targeting integrated bioactive glasses hydrogel for treatment of breast cancer bone metastasis
Author: Chengkuan Liu a b , Yangui Zhong a b , Haibo Huang a b
Non‐invasive diagnosis and surveillance of bladder cancer with driver and passenger DNA methylation in a prospective cohort study
Author: Yu Xiao 1 2, Lingao Ju 3, Kaiyu Qian 1 2
Manganese induces tumor cell ferroptosis through type-I IFN dependent inhibition of mitochondrial dihydroorotate dehydrogenase
Author: Shanlong Zhang 1, Li Kang 2, Xiaoxue Dai 3
Regulatory factor X1 induces macrophage M1 polarization via promoting DNA demethylation in autoimmune inflammation
Author: Shuang Yang, Pei Du, Haobo Cui
IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages
Author: Lei Zhao, ∙ Zonghan Wang, ∙ Yuying Tan
Nrf2 regulates the activation of THP-1 cells induced by chloral hydrate
Author: Jinfeng Zhao, Shiyu Yan, Xue Ma
EID3 Promotes Cancer Stem Cell-Like Phenotypes in Osteosarcoma through the Activation of PI3K-AKT Signaling Pathway
Author: Yan Wang, Shiyong Luo, Yuxuan Wang
Surface Engineering of HEK293 Cell-Derived Extracellular Vesicles for Improved Pharmacokinetic Profile and Targeted Delivery of IL-12 for the Treatment of Hepatocellular Carcinoma
Author: Jing Zhang 1, Haijing Song 2, Yanan Dong 1
Mesenchymal Stem Cell Derived Exosomes as Nanodrug Carrier of Doxorubicin for Targeted Osteosarcoma Therapy via SDF1-CXCR4 Axis
Author: Hongxiang Wei, Fei Chen, Jinyuan Chen
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells
Author: Jing Cheng, Yutong Wang, Lizheng Yin
E7-Targeted Nanotherapeutics for Key HPV Afflicted Cervical Lesions by Employing CRISPR/Cas9 and Poly (Beta-Amino Ester)
Author: Jinfeng Xiong, Songwei Tan, Long Yu
Decreased RNA m6A methylation enhances the process of the epithelial mesenchymal transition and vasculogenic mimicry in glioblastoma
Author: Min Tao, Xiaoyu Li, Lei He1
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CNKSR2 interactome analysis indicates its association with the centrosome/microtubule system
Author: Lin Yin, Yalan Xu, Jie Mu
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OGT mediated HDAC5 O-GlcNAcylation promotes osteogenesis by regulating the homeostasis of epigenetic modifications and proteolysis
Author: Yu Du a , Xiang Gao a b c , Jianqiang Chen b
Rab5c promotes RSV and ADV replication by autophagy in respiratory epithelial cells.
Author: Xiuli Wang, Jing Cheng, Linchao Shen
Epstein-Barr Virus Induces Lymphangiogenesis and Lympth Node Metastasis via Upregulation of VEGF-C in Nasopharyngeal Carcinoma
Author: Deng-Ke Li, Xing-Rui Chen, Li-Na Wang
Serine/Threonine kinase 16 phosphorylates STAT3 and confers a JAK2-Inhibition resistance phenotype in triple-negative breast cancer
Author: Zhenyun Zhu , Qin Xiang ，Shuangqiong Li，Chen Chen，Jian Shi
Metformin Alleviates Hepatic Steatosis and Insulin Resistance in a Mouse Model of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease by Promoting Transcription Factor EB-Dependent Autophagy
Author: Dan Zhang1†, Yicheng Ma2†, Jianjun Liu3†
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FOSL2 Is Involved in the Regulation of Glycogen Content in Chicken Breast Muscle Tissue
Author: Xiaojing Liu, Lu Liu, Jie Wang
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β-Asarone Attenuates Aβ-Induced Neuronal Damage in PC12 Cells Overexpressing APPswe by Restoring Autophagic Flux
Author: Zhenwan Li, Jin Ma, Zhongsheng Kuang andYong Jiang*
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Targeting MDK Abrogates IFN-γ-Elicited Metastasis inCancers of Various Origins
Author: Luyu Zheng, 1, † Qun Liu
MicroRNA-302a promotes neointimal formation following carotid artery injury in mice by targeting PHLPP2 thus increasing Akt signaling
Author: Ying-ying Liu, Xiu Liu, Jia-guo Zhou and Si-jia Liang
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BRG1 alleviates microglial activation by promoting the KEAP1-NRF2/HO-1 signaling pathway and minimizing oxidative damage in cerebral ischemia–reperfusion
Author: Kongwei Guo, Yanxing Shang, Zhao Wang
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Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Promotes Viability of Rheumatoid Arthritis Fibroblast-Like Synoviocytes
Author: Yong Chen, Baojiang Wang, Yanjuan Chen
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Fenofibrate improves hepatic steatosis, insulin resistance, and shapes the gut microbiome via TFEB-autophagy in NAFLD mice
Author: Dan Zhang, Yicheng Ma, Jianjun Liu
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Glycyrrhizic acid alleviated MI/R-induced injuries by inhibiting Hippo/YAP signaling pathways.
Author: Xian Cheng, Yanwu Liu, Bingcai Qi
Combined Usage of MDK Inhibitor Augments Interferon-γ Anti-Tumor Activity in the SKOV3 Human Ovarian Cancer Cell Line
The sugar moiety in protopanaxadiol ginsenoside affects its ability to target glucocorticoid receptor to regulate lipid metabolism
Author: Weili Li, Lujuan Zheng, Xiao Ma
Single-cell RNA-seq analysis of rat molars reveals cell identity and driver genes associated with dental mesenchymal cell differentiation
Author: Yingchun Zheng, Ting Lu, Leitao Zhang
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Uricase-Expressing Engineered Macrophages Alleviate Murine Hyperuricemia
Author: Yu-Zhong Feng ,†,Hao Cheng ,†,Guo-Qing Xiong ,Jia-Zhen Cui ,Zhi-Li Chen ,Yuan-Yuan Lu ,Zhi-Xin Meng ,Chen Zhu ,Hao-Long Dong ORCID,Xiang-Hua Xiong ,Gang Liu ,Qing-Yang Wang ,* andHui-Peng Chen ,*
TXNIP positively regulates the autophagy and apoptosis in the rat müller cell of diabetic retinopathy
Author: Haocheng Ao, Haichun L, Xiujuan Zhao
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CAPG interference induces apoptosis and ferroptosis in colorectal cancer cells through the P53 pathway
Author: Yingying Zhao, Rui Ma, Chuyue Wang
Metformin suppresses lung adenocarcinoma by downregulating long non-coding RNA (lncRNA) AFAP1-AS1 and secreted phosphoprotein 1 (SPP1) while upregulating miR-3163
Author: Caiyu Qiua, *, Chuanxiang Lib
Galectin-3 enhances trastuzumab resistance by regulating cancer malignancy and stemness in HER2-positive breast cancer cells
Author: Yuqiu Chen, Jiawei Xu, Wang Pan
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Cabazitaxel suppresses colorectal cancer cell growth via enhancing the p53 anti-tumor pathway
Author: Wen Zhang, Ruiqian Sun, Yongjun Zhang
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RNA Binding Protein RNPC1 Suppresses the Stemness of Human Endometrial Cancer Cells via Stabilizing MST1/2 mRNA
Author: XingMei Wu, YongHui Wang, WeiJuan Zhong
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Distinguishing High-Metastasis-Potential Circulating Tumor Cells through Fluidic Shear Stress in a Bloodstream-Like Microfluidic Circulatory System
Author: Michael Yang, Wenxiu LI, Zhengjun Guo
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Caffeic acid phenethyl ester promotes oxaliplatin sensitization in colon cancer by inhibiting autophagy
Author: Fei Xing, Ning Liu, Can Wang
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N6-methyladenosine reader RBMX is essential for motor cortex excitatory neuron survival in amyotrophic lateral sclerosis
Author: di he, Qiing Liu, Liyang Liiu
Self-DNA accumulation as a risk factor for accelerating the pathogenesis of rheumatoid arthritis in elderly individuals
Author: Weidan Luo, Vincent Kam Wai Wong
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