Acetate reprogrammes tumour metabolism and promotes PD-L1 expression and immune evasion by upregulating c-Myc
Author: Juhong Wang, Yannan Yang, Fei Shao
Interpretation >
Adaptive Design of Nanovesicles Overcoming Immunotherapeutic Limitations of Chemotherapeutic Drugs through Poliovirus Receptor Blockade.
Author: Yongkang Yu, Fan Zhang, Wenqing Xiao
Interpretation >
Cell surface patching via CXCR4-targeted nanothreads for cancer metastasis inhibition
Author: Minglu Zhou, Chendong Liu, Bo Li
Interpretation >
Vitamin D binding protein (VDBP) hijacks twist1 to inhibit vasculogenic mimicry in hepatocellular carcinoma.
Author: Lu-ning Qin, Heng Zhang, Qing-qing Li
Subcutaneous checkpoint inhibition is equivalent to systemic delivery when combined with nelitolimod delivered via pressure-enabled drug delivery for depletion of intrahepatic myeloid-derived suppressor cells and control of liver metastases
Author: Chandra C Ghosh, Lauren Cournoyer, Yujia Liu
Biomimetic MDSCs membrane coated black phosphorus nanosheets system for photothermal therapy/photodynamic therapy synergized chemotherapy of cancer
Author: Zhou Lan, Wei-Jia Liu, Wu-Wei Yin
Discovery of a peptide proteolysis-targeting chimera (PROTAC) drug of p300 for prostate cancer therapy
Author: Dize Zhang, Bohan Ma, Donghua Liu
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A Macrophage Membrane–Polymer Hybrid Biomimetic Nanoplatform for Therapeutic Delivery of Somatostatin Peptide to Chronic Pancreatitis
Author: Fang Wang 1, 2, †ORCID
The effect of the nucleolar protein ZNF385A on the ribosomal DNA copy number variation in response to Cr(VI)-induced DNA damage
Author: Huadong Xu , Fan Wu , Chan Ding
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Burdock miR8175 in diet improves insulin resistance induced by obesity in mice through food absorption
Author: Huichen Song ，Huanhuan Shi ，Mengru Ji ，Jiaqi Ding，Lin Cong，Silin Chen，Jiahui Zhou，Xinyan Zha，Jinyang Ye，Runcheng Li，Xiaoyu Hou，Siyu Mao，Xiaohong Jiang，Wen Zhang，Jing Li，Yujing Zhang
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Whitening of brown adipose tissue inhibits osteogenic differentiation via secretion of S100A8/ A9
Author: Ting Wang, Chaoran Zhao, Jiahuan Zhang
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FOSL2 Is Involved in the Regulation of Glycogen Content in Chicken Breast Muscle Tissue
Author: Xiaojing Liu, Lu Liu, Jie Wang
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Inhibition of leucine-rich repeats and calponin homology domain containing 1 accelerates microglia-mediated neuroinflammation in a rat traumatic spinal cord injury model
Author: Wen-Kai Chen； Lin-Juan Feng； Qiao-Dan Liu；Qing-Feng Ke, Pei-Ya Cai, Pei-Ru Zhang
Interpretation >
Enhanced NK cell activation via eEF2K-mediated potentiation of the cGAS–STING pathway in hepatocellular carcinoma
Author: Yan Xu, Fang Sun, Yuying Tian
Slight up-regulation of Kir2.1 channel promotes endothelial progenitor cells to transdifferentiate into a pericyte phenotype by Akt/mTOR/Snail pathway
Author: Xiaodong Cui, Xiaoxia Li, Yanting He
Interpretation >
Inhibition of autophagy suppresses SARS-CoV-2 replication and ameliorates pneumonia in hACE2 transgenic mice and xenografted human lung tissues
Author: Chao Shang，Xinyu Zhuang，He Zhang， Yiquan Li， Yilong Zhu， Jing Lu，Chenchen Ge，Jianan Cong，Tingyu Li，Nan Li，Mingyao Tian，Ningyi Jin, and Xiao Li
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Toxoplasma gondii microneme protein MIC3 induces macrophage TNF-α production and Ly6C expression via TLR11/MyD88 pathway
Author: Jingfan Qiu, Yanci Xie, Chenlu Shao
TGM2 inhibits the proliferation, migration and tumorigenesis of MDCK cells
Author: Zhenyu Qiu, Shouqing Guo, Geng Liu
A non‐canonical role of endothelin converting enzyme 1 (ECE1) in promoting lung cancer development via directly targeting protein kinase B (AKT).
Author: Li Chen, Yikai Lu, Mengmeng Zhao
Shenqi Sanjie Granules induce Hmox1-mediated ferroptosis to inhibit colorectal cancer.
Author: Meng Chena,Shengli Ma， Wenbo Ji， Weihua Hud ∙ Jiguang Gaoa，Jianke Yanga， Yu Liub, Qianwen Cuib,Shasha Yang， Xiaohui Xua， Haiming Daib,∙ Lei Hu
Multi-omics profiling reveals dysregulated ribosome biogenesis and impaired cell proliferation following knockout of CDR2L
Author: Eirik Tveit Solheim, Yola Gerking, Torbjørn Kråkenes
PET imaging of an optimized anti-PD-L1
probe 68Ga-NODAGA-BMS986192
in immunocompetent mice and non-human
primates
Author: Huimin Zhou1, Guangfa Bao1, Ziqiang Wang1
Long noncoding RNAs AC026904.1 is essential for TGF-β-induced migration and epithelial-mesenchymal
transition through functioning as an enhancer of Slug in lung cancer cells
Author: Jie Yao, Xiaochen Lu, Yuxuan Wang
Establishment of a Mouse Model for Porokeratosis Due to Mevalonate Diphosphate Decarboxylase Deficiency
Author: Kexin Peng, Wenghong Wong, Qiaoan Zhang
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Super-enhancers reorganization controls re-sensitization of oxaliplatin-resistant FBXW7-mutated colorectal cancer
Author: Eros Di Giorgio，Vanessa Tolotto，Nicolò Gualandi，Monica Colitti，Raffaella Picco，Ylenia Cortolezzis，Francesca D'Este，Mariachiara Gani，Wayne Hancock，Giovanni Terrosu，Cristina Degrassi，Claudio Brancolini，Luigi Xod
Analysis and identification of mitochondrial DNA associated with age-related hearing loss
Author: Tianyu ma，Xiaoyun Zeng，Mengting Liu，Shijia Xu，Yuyao Wang，Qilong Wu，Tianhong Zhang
A receptor-independent signaling pathway for BDNF
Author: Julia Fath, Franck Brouillard, Alexandre Cabaye
